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Beneficial effect of a novel pentadecapeptide BPC 157 on gastric lesions induced by restraint stress, ethanol, indomethacin, and capsaicin neurotoxicity

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The peptide functions as a precision senolytic agent by competing with endogenous FOXO4 for p53 binding, releasing the tumor suppressor protein to trigger apoptosis specifically in cells that have accumulated the senescence-associated secretory phenotype (SASP) markers